Do Men who have Sex with Men (MSM) in the United States Understand that HIV Serodiscordance is Possible?
Bradley H. Wagenaar1, Kristina L. Grabbe2, Rob Stephenson3, Christine M. Khosropour1, Patrick S. Sullivan*, 1
Identifiers and Pagination:Year: 2013
First Page: 14
Last Page: 16
Publisher Id: TOAIDJ-7-14
Article History:Received Date: 29/11/2012
Revision Received Date: 26/4/2013
Acceptance Date: 29/4/2013
Electronic publication date: 20/9/2013
Collection year: 2013
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Little is currently known about the extent to which US MSM understand the possibility that a long-term sex partner can have an HIV status different than one’s own status. This information is important in the adaptation of Couples Voluntary HIV Counseling and Testing (CVCT) for US MSM.
428 US MSM completed an online survey using MySpace.com from March-April, 2009.
Of 426 MSM with complete data, 21.1% (90) were not definitively aware that serodiscordance is possible. Factors associated with a lack of understanding that serodiscordance is possible were: never having tested for HIV (OR: 2.0; CI: 1.1, 3.8), compared to testing 0-6 months previously and having a high school education or less (OR: 2.2; CI: 1.1, 4.5), compared to men who had completed at least some college.
A large proportion of young, internet-using MSM in the United States may not understand that HIV serodiscordance is possible within sexual partnerships. Based on these results, we recommend that CVCT provided to male couples in the United States should include education on HIV serodiscordance.
Men who have sex with men (MSM) continue to represent the majority of all new HIV diagnoses in the United States (US); developing and testing interventions to serve MSM is a high priority for HIV prevention [1,2]. Couples Voluntary Counseling and Testing (CVCT) is an African testing service that has been recently adapted for use with US male couples who have also expressed high levels of hypothetical willingness to participate in CVCT [3,4]. The African CVCT intervention includes an educational component to help couples understand that HIV serodiscordance is possible – that is, that one partner may be HIV-positive while the other is HIV-negative. It is not clear whether MSM in the US would also benefit from education about the possibility of HIV serodiscordance in the adapted CVCT intervention for MSM. Limited available data suggest that MSM tend to assume HIV partner concordance [5,6]; MSM are more likely to engage in unprotected anal intercourse (UAI) with partners who are perceived to share the same HIV serostatus, compared to those who are HIV discordant or whose status they do not know [7,8].
Data were from the 3-month follow-up time point of an online HIV prevention research study for US MSM. Methods have been previously reported . Briefly, MSM were recruited online from MySpace.com from March-April, 2009 in the US. Men who were white, black, or Hispanic and who consented to prospective follow-up were invited to participate in a 3-month follow-up survey July-August, 2009.
In addition to demographic and behavioral information, the survey collected data on men’s understanding of the possibility of HIV serodiscordance, measured using responses to the statement: “in a couple that has been having sex for several years, if one partner is HIV-negative the other partner is also HIV-negative.” Men who responded “false” were considered to understand that serodiscordance is possible; others were considered not to understand. Using logistic regression in SAS 9.3 (Cary, NC), we calculated crude odds ratios and 95% confidence intervals (CI) for the associations of understanding that serodiscordance is possible with selected demographic characteristics and sexual risk behaviors. Two-tailed Wald tests and an alpha level of 0.05 were used for significance testing.
From 428 total survey respondents, we excluded one man with missing data and one man responding “prefer not to answer” to the serodiscordance question. Most respondents were between 18-24 years of age, and over 75% had a main male sex partner in the last 12 months (Table 1). Over 70% of respondents reported UAI in the last 12 months. nearly half had received and HIV test in the last 12 months and about a quarter had never been tested for HIV. Over 30% did not know their most recent male sex partner’s HIV status.
Characteristics Associated with Not Understanding that HIV Serodiscordance is Possible Among 426a US MSM, 2009
n (%) Unless Notedb
|Total||426 (100)||336 (78.9)||90 (21.1)|
|Non-Hispanic White||203 (47.7)||162 (79.8)||41 (20.2)||1 (reference)|
|Non-Hispanic Black||61 (14.3)||45 (73.8)||16 (26.2)||1.4 (0.72, 2.7)|
|Hispanic||162 (38.0)||129 (79.6)||33 (20.4)||1.0 (0.61, 1.7)|
|Age||22 (median), 6 (IQR)|
|18-24||284 (66.7)||224 (78.9)||60 (21.1)||1 (reference)|
|25-29||87 (20.4)||71 (81.6)||16 (18.4)||0.84 (0.46, 1.6)|
|Over 30||55 (12.9)||41 (74.6)||14 (25.5)||1.3 (0.65, 2.5)|
|College, post graduate, or professional school||88 (20.7)||76 (86.4)||12 (13.6)||1 (reference)|
|Some college, associate's or technical degree||206 (48.4)||162 (78.6)||44 (21.4)||1.7 (0.86, 3.4)|
|High school or less||129 (30.3)||98 (74.2)||34 (25.8)||2.2 (1.1, 4.5)*|
|Missing||3 (0.70)||2 (66.7)||1 (33.3)|
|Midwest||67 (15.7)||54 (80.6)||13 (19.4)||1 (reference)|
|North||66 (15.5)||50 (75.8)||16 (24.2)||1.3 (0.58, 3.0)|
|South||133 (31.2)||107 (80.5)||26 (19.5)||1.0 (0.48, 2.1)|
|West||141 (33.1)||112 (79.4)||29 (20.6)||1.1 (0.52, 2.2)|
|Missing||19 (4.5)||13 (68.4)||6 (31.6)|
|Had a main male sex partner in last 12 months|
|No||103 (24.2)||78 (75.7)||25 (24.3)||1 (reference)|
|Yes||323 (75.8)||258 (79.9)||65 (20.1)||0.79 (0.46, 1.3)|
|Most recent male sex partner's HIV status|
|Negative||266 (62.4)||212 (79.7)||54 (20.3)||1 (reference)|
|Positive||17 (4.0)||13 (76.5)||4 (23.5)||1.2 (0.38, 3.9)|
|Unknown||143 (33.6)||111 (77.6)||32 (22.4)||1.1 (0.69, 1.9)|
|Had unprotected anal intercourse in last 12 months|
|No||121 (28.4)||98 (81.0)||23 (19.0)||1 (reference)|
|Yes||305 (71.6)||238 (78.0)||67 (22.0)||1.2 (0.71, 2.0)|
|Number of male sex partners in last 12 months||4 (median), 5 (IQR)|
|1||83 (19.5)||66 (79.5)||17 (20.5)||1 (reference)|
|2 - 3||115 (27.0)||85 (73.9)||30 (26.1)||1.4 (0.70, 2.7)|
|4 - 7||123 (28.9)||101 (82.1)||22 (17.9)||0.85 (0.42, 1.7)|
|>7||105 (24.6)||84 (80.0)||21 (20.0)||0.97 (0.47, 2.0)|
|Time since last HIV test|
|0-6 months||112 (26.3)||90 (80.4)||22 (19.6)||1 (reference)|
|7-12 months||84 (19.7)||71 (84.5)||13 (15.5)||0.75 (0.35, 1.6)|
|>12 months||91 (21.4)||74 (81.3)||17 (18.7)||0.94 (0.47, 1.9)|
|Never tested||100 (23.5)||67 (67.0)||33 (33.0)||2.0 (1.1, 3.8)*|
|Un known||39 (9.2)||34 (87.2)||5 (12.8)||0.60 (0.21, 1.7)|
* P < .05 (Wald X2)
a From 428 total respondents, excludes one man with missing data and one man responding “prefer not to answer” regarding the statement: “In a couple that has been having sex for several years, if one partner is HIV-negative the other partner is HIV-negative.”
b Percentages in this column reflect column percentages. For example, 47.7% of our sample was of Non-Hispanic White race/ethnicity. All other columns are row percentages pertaining to percent responding “correctly” or “incorrectly” to the serodiscordance question.
c Includes 49 men responding “true” and 41 responding “don’t know” regarding the statement: “In a couple that has been having sex for several years, if one partner is HIV-negative the other partner is HIV-negative.”
Abbreviations: OR, Odds Ratio; HIV, Human immunodeficiency virus; IQR, Interquartile range.
Of 426 men included in the analysis, 21.1% (90) of MSM were not aware that serodiscordance is possible: 11.5 percent (49) responded “true” and 9.6% (41) responded “I don’t know” to the question about serodiscordance. The odds of not understanding that serodiscordance is possible were 2.0 (CI: 1.1, 3.8) times as high for men who had never tested for HIV, compared to the odds for men who had tested for HIV 0-6 months previously. Additionally, the odds of not understanding that serodiscordance is possible were 2.2 (CI: 1.1-4.5) times as high among men with a high school education or less, compared to the odds for men who had completed at least some college.
A substantial proportion of young, internet-using MSM in the United States may not understand that HIV serodiscordance is possible within sexual partnerships. Lack of understanding may occur especially among men not previously tested for HIV and those with less educational attainment. These same factors have been recently reported to be associated with lower levels of general HIV knowledge .
We recognize several important limitations to our work. First, we were limited to a single item for this assessment, and the measure is imperfect. We considered respondents who answered “I don’t know” to not be aware of the possibility of serodiscordance. However, even if we only considered those who endorsed the item as true as not being aware of the possibility of serodiscordance, our primary conclusion - that an important proportion of young MSM are not definitively certain that serodiscordance is possible - is still valid. We also acknowledge that our sample is not representative of all US MSM, or all internet-using MSM.
Based on these results, we recommend that CVCT provided to male couples in the United States should include education on HIV serodiscordance. Since approximately one in six MSM who had been previously tested for HIV also did not recognize the possibility of serodiscordance, this concept might also be important to include in general HIV/AIDS educational interventions and standard prevention counseling with individuals receiving HIV counseling and testing.
CONFLICT OF INTEREST
The authors confirm that this article content has no conflict of interest.
The authors would like to thank Nicole Luisi for her expert support and data management.
This work was supported by the Center for AIDS Research at Emory University (P30 AI050409) and the National Institute on Minority Health and Health Disparities (RC1MD004370).
The findings and conclusions in this article are those of the authors and do not necessarily represent the official position of the US Centers for Disease Control and Prevention.