RESEARCH ARTICLE


Fatal Fast-Evolution of Nasopharyngeal Squamous Cell Carcinoma in an HIV Patient with EBV and HPV (-16 AND -33) in Blood Serum



Guillem Sireraa, b, Sebastià Videla*, b , Joan Romeua, b, MariPaz Cañadasc, Maria-Teresa Fernándezd, Susana Baloa, Beatriz Cirauquie, Laila Darwichf, Celestino Rey-Jolya, Bonaventura Cloteta, b, f
a HIV Clinical Unit, Department of Medicine
b Lluita Contra La SIDA Foundation
d Department of Pathology
e Department of Oncology; University Hospital Germans Trias i Pujol, Badalona (Barcelona); Universitat Autònoma de Barcelona (U.A.B.)
c GeneralLab, Barcelona
f Retrovirology Laboratory IrsiCaixa, Spain


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2008 Bentham Science Publishers Ltd.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

* Address correspondence to this author at the Lluita Contra La SIDA Foundation; Hospital Universitari Germans Trias i Pujol; Badalona, Barcelona-08916, Spain; Fax: (34) 93 465 76 02; E-mail: svidela@esteve.es


Abstract

Our case illustrates the first report of an HIV-infected patient with a nasopharyngeal squamous cell carcinoma with viremia by one Epstein-Barr virus (EBV) and seropositivity by two high risk oncogenic human papilloma viruses (HPV)-types (HPV-16 and HPV-33), previous to his death. This patient presented a fatal fast-evolution.