Aims and Scope
Recent Articles
Pre-exposure Prophylaxis and Post-exposure Prophylaxis Awareness among Men Who Have Sex with Men in Brazil: A National Survey
Artur Acelino Francisco Luz Nunes Queiroz, Alvaro Francisco Lopes de Sousa, Layze Braz de Oliveira, Odinéa Maria Amorim Batista, Sónia Dias and Isabel Amélia Costa Mendes
The Open AIDS Journal, 2024; 18: e18746136283427.
Electronic Publication Date: March 04, 2024
Important Risk Factors of Liver Cirrhosis in HIV and Hepatitis C Coinfected Patients: A Systematic Review
Esmaeil Mehraeen, Nazanin Janfaza, Ramin Shahidi, Arian Afzalian, Sanaz Varshochi, Reyhaneh Jashaninejad, Ava Pashaei, Marcarious M. Tantuoyir, Muhammed Camara, Parinaz Paranjkhoo, Zohal Parmoon, Shahmohamadi Elnaz, Roghayeh Salmani, Parisa Matini, Pegah Mirzapour, Hooman Ebrahimi, Ali Moradi, SeyedAhmad SeyedAlinaghi and Shayesteh Jahanfar
The Open AIDS Journal, 2024; 18: e18746136280350.
Electronic Publication Date: February 29, 2024
Editor's Choice
High Prevalence of Lower Extremity Medial Arterial Calcification in HIV-infected Patients With and Without Chronic Renal Disease: A Vascular Ultrasound Cross-sectional Study
Klaudija Višković, Annibale Marinelli, Katrin Nedeljko, Petra Povalej Bržan, Nikolina Bogdanić, Josip Begovac
Background:
The association between HIV infection and increased risk of atherosclerotic peripheral artery disease (PAD) has been documented. Still, the relationship between HIV infection and lower extremity medial arterial calcification (MAC) is unknown.
Objective:
We performed a cross-sectional study to compare the frequency of MAC diagnosed by vascular ultrasound in PAD-asymptomatic people living with HIV (PLWH) with and without chronic kidney disease (CKD) compared to HIV-uninfected participants as a control group.
Methods:
MAC was defined as smooth, linear, and non-stenotic hyperechogenicity in the arterial wall compared to the surrounding tissues. We studied 191 patients: 50 PLWH (25 with an estimated glomerular filtration rate (eGFR) ≥60 mL/min/1.73m2 and 25 with an eGFR <60 mL/min/1.73m2) and 141 HIV-uninfected patients (68 with eGFR<60 ml/min/1.73m2).
Results:
MAC was most frequently found in PLWH with CKD (76%). The prevalence of MAC among PLWH was 54.0% (95% confidence interval [CI], 40.4-67.0%), whereas, in HIV-uninfected, it was 34.0% (95% CI, 26.7-42.2%, P=0.013). Age and CKD were consistently associated with MAC in our multivariable models, and there was also a sign that PLWH had higher odds of having MAC.
Conclusion:
We found a higher prevalence of MAC in PAD-asymptomatic PLWH compared to HIV-uninfected ones and provided evidence that HIV infection could be associated with MAC.
January 16, 2023
Other Post
- April 27, 2023
Public Awareness and Stigmatizing Attitudes toward People Living with Human Immunodeficiency Virus Acquired Immune Deficiency Syndrome in Saudi Arabia
July 25, 2023
HIV RNA and HCV RNA Levels, and Mortality: The Japan Cohort Study of HIV Patients Infected through Blood Products
July 13, 2021
Association between Higher CD32a+CD4+ T Cell Count and Viral Load in the Peripheral Blood of HIV-infected Patients
May 23, 2020
Preclinical Assessment of a Cartridge-Based Flow-Through Assay for Determination of Adult CD4 T-Cell Count
May 31, 2019
Immunologic Restoration of People Living with Human Immunodeficiency Virus on Highly Active Anti-retroviral Therapy in Ethiopia: The Focus of Chronic Non-Communicable Disease Co-Morbidities
April 30, 2019
Inconsistent Use of Condom in Italian HIV-Serodiscordant Heterosexual Couples as Revealed by the Detection of Y Chromosomal (Yc) DNA in Vaginal Swabs
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